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(e.g. ER/AP-1, ER/SP1, ER/NF-kB)

(ER/ERE)

As part of the Integrative Cancer Biology Program of the National Cancer Institute, we are developing an integrative computational and high-throughput experimental approach to characterize the epigenetic mechanisms involved in the target genes of the ER pathway. ERTargetDB integrates information from the ongoing Chip-on-chip experiments in our laboratory and promoter sequence conservation from the OMGProm database. We will add methylation and acetylation patterns across the target gene promoters in the future versions of the database. Read more....

Victor X. Jin, Hao Sun, Twyla T. Pohar et al. ERTargetDB: an integral information resource of transcription regulation of ER target genes (Accepted by the Journal of Molecular Endocrinology). Supplementary Tables